Nephrotoxicity of contrast media

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Contrast Media: Are There Differences in Nephrotoxicity among Contrast Media?

Iodinated contrast agents are usually classified based upon their osmolality--high, low, and isosmolar. Iodinated contrast agents are also nephrotoxic in some but not all patients resulting in loss of glomerular filtration rate. Over the past 30 years, nephrotoxicity has been linked to osmolality although the precise mechanism underlying such a link has been elusive. Improvements in our underst...

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*Corresponding author: Majid Tavafi, Department of anatomy, Faculty of Medicine, Lorestan University of Medical sciences, Khoram Abad, Iran. E-mail: [email protected] Radiological procedures using injection of contrast media have been employed increasingly for diagnostic purposes (1). Nevertheless, side effect of contrast media injection known as contrast media nephrotoxicity is still a major c...

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Prophylaxis of Contrast-Induced Nephrotoxicity

Contrast-induced nephrotoxicity (CIN) is a form of acute kidney injury that follows intravascular contrast media exposure. CIN may be preventable because its risk factors are well established and the timing of renal insult is commonly known in advance. However, contrast-induced nephrotoxicity is still the third leading cause of iatrogenic renal failure. This important complication accounts up t...

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Re: Contrast media-induced nephrotoxicity: identification of patients at risk and algorithms for prevention.

Editor: I found the recent article by Waybill and Waybill (1) extremely helpful in the management of patients at risk for contrast-induced nephropathy. I have two questions for the authors. First, what are their recommendations regarding acetylcysteine? A recent report in the New England Journal of Medicine by Tepel et al (2) demonstrated decreased nephrotoxicity in patients undergoing infused ...

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Acetylcysteine and contrast agent-associated nephrotoxicity.

OBJECTIVES Prophylactic acetylcysteine along with hydration seems to be better than hydration alone in preventing the reduction in renal function induced by a contrast dye. BACKGROUND Contrast media can lead to acute renal failure that may occasionally require hemodialysis. METHODS One hundred eighty-three consecutive patients with impairment of renal function, undergoing coronary and/or pe...

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ژورنال

عنوان ژورنال: Kidney International

سال: 1989

ISSN: 0085-2538

DOI: 10.1038/ki.1989.254